FORMALDEHYDE FORMATION IN THE GLYCINE CLEAVAGE SYSTEM AND ITS USE FOR AN ALDOLASE-BASED BIOSYNTHESIS OF 1,3-PRODANEDIOL

Formaldehyde formation in the glycine cleavage system and its use for an aldolase-based biosynthesis of 1,3-prodanediol

Abstract Glycine cleavage system (GCS) occupies a key position in one-carbon (C1) metabolic pathway and receives great attention for the use of C1 carbons like formate and CO2 via synthetic biology.In this work, we demonstrate that formaldehyde exists as a substantial byproduct of the GCS reaction cycle.Three causes are Socks identified for its for

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Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division

Abstract Selective inheritance of sub-cellular components has emerged as a mechanism guiding stem cell fate after asymmetric cell divisions.Peroxisomes play a crucial role in multiple metabolic processes such as fatty acid metabolism and reactive oxygen species detoxification, but the apportioning of peroxisomes during stem cell Computer Data divis

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